This report analyzes the worldwide markets for Biochips in US$ Million by the following Product Segments: DNA Chips, Protein Chips, and Lab Chips. Annual estimates and forecasts are provided for the period 2009 through 2017. Also, a six-year historic analysis is provided for these markets. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia Pacific, Middle East, and Latin America. The report profiles 77 companies including many key and niche players such as Affymetrix Inc., Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Caliper Life Sciences, Inc., Cepheid Inc., Fluidigm Corporation, GE Healthcare Ltd., Illumina, Inc., Life Technologies Corporation, Ocimum Biosolutions Ltd., Takara Bio, Inc., Clontech Laboratories, Inc., and Zyomyx, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain.
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-3
Quantitative Techniques & Analytics I-3
Product Definitions and Scope of Study I-3
A. DNA Chips I-3
B. Protein Chips I-4
C. Lab Chips I-4
II. EXECUTIVE SUMMARY
1. INDUSTRY OVERVIEW II-1
A Primer II-1
Recession Dries Up Funds for Biotech Firms II-1
Promising Biochips Promote Biological Research II-2
Key Forces Driving the Industry II-3
DNA Chips Lead the Application Front II-3
Protein Biochips - Set for Robust Expansion II-3
Lab-on-a-Chips: Fusion of Nanotechnology & Genetic Engineering II-4
Industry Challenges II-4
Standardization: A Key Challenge II-4
Price Dearness Pauses Biochips Growth II-5
2. MARKET DYNAMICS II-6
Current Approaches to Biochips II-6
The Business of Biochips II-6
Technological Differentiation in Demand II-7
Focus on Highly Intelligent Diagnostic Systems II-7
Scalability & Pricing - Focus Areas II-7
Biochips: Expanding Role in Diagnostic Medicine II-8
Advancements in Biochip Technology II-8
Biochip Technology Boosts Personalised Medicine II-9
Biochip Technology Spreads beyond Pharma Industry II-9
Proteomics "Chip" into Biochip Technology II-10
Towards Increasing Minaturization II-10
Technological Trends II-10
Sensitivity II-10
Microfabrication II-10
Density II-11
Integrated Chips II-11
Patent Trends II-11
Table 1: Number of Lab-on-a-Chip Patents (includes
corresponding Graph/Chart) II-11
Table 2: % of Lab-on-a-Chip Patent Documents by
Country/Authority of Origin (January 2008 - April 2009)
(includes corresponding Graph/Chart) II-12
Table 3: Number of Lab-on-a-Chip Documents by Patent
Assignees (January 2008 - April 2009) (includes
corresponding Graph/Chart) II-12
Patent Applications II-13
3. COMPETITION II-14
Industry Structure II-14
Major Participants II-14
Affymetrix: A Major Market Player II-14
Growing Partnerships between Pharma and Biotech Companies II-14
Tech Giants Join the Biochip Fray II-15
4. PRODUCT OVERVIEW II-17
Biochips - Complex Blend of Biochemistry and Electronics II-17
Historical Perspective II-17
Lab-on-a-chip: An Enabled Technology II-19
Utility II-19
Evolution and Segmentation II-19
Differing Perspectives II-19
Classification of Biochips II-20
Need for Biochips II-21
Manufacturing Systems Used in Biochip Manufacture II-21
Working of a Biochip II-22
DNA Transcription & Translation Through A Biochip II-22
A Functional Model II-22
Cocktail of Disparate Technically Specialized Applications II-23
Biochips: By-product of Multi-disciplinary Sciences II-23
Nanotechnology II-23
BioMEMS II-23
Microfluidics II-24
Micro Total Analysis System II-24
5. BIOCHIP AND MICROARRAY CONSTRUCTION II-26
Chip Architecture II-26
Essence of a Biochip II-26
Concept of a Microarray II-26
Microarray Modules II-26
High Degree of Automation Spurs Biochips Use II-27
Microfabrication Technology in Biochips made from Polymer and
Plastics II-27
Micro-optics in Biochips II-28
Liquid Handling Through Micro-Dispensers II-28
Capillary Electrophoresis and Electrochemical Detectors II-28
Other Technologies II-28
Management of Bio-information II-28
Scanning II-29
Microarray Database Management II-29
Classification of DNA Chips II-29
General Description of Spotted cDNA Microarrays II-29
Spotted DNA Arrays II-30
Spotted cDNA Versus Spotted Oligonucleotide Arrays II-30
Limitations of Conventional cDNA Microarrays II-30
Protein Biochips II-31
General Applications of Protein Biochips II-31
Challenges in the Design of a Protein Biochip II-32
Limitations of Protein Chip Technology II-32
Concluding Remarks for Protein Biochips II-33
6. APPLICATIONS OF BIOCHIPS II-34
Biochip Uses II-35
Pharmaceutical Investigation II-35
Medical Diagnostics II-35
Advantages of Biosensor Chip Technology II-36
Forensics II-36
Transplantation Screening II-36
Identity Testing II-36
Water and Environmental Testing II-37
Food Industry II-37
7. PRODUCT INNOVATIONS/INTRODUCTIONS II-38
Randox Launches Evidence Evolution Analyzer II-38
South Korea Develops Instant Microfluidic Biochip II-38
Fluidigm Introduces Reusable FR48.48 Dynamic Array™ IFC II-38
Cellix Introduces Vena4Y™ and Vena4Y2™ Biochips II-38
Agilent Technologies Unveils Workflow HPLC-Chip II-39
Febit Holding Introduces First Human Cancer Biochip II-39
Blue4Green Rolls Out Lab-on-a-chip Solution II-40
Randox Laboratories Unveils Biochip Arrays II-40
Randox Laboratories Introduces Evidence Investigator II-40
Randox Unveils Innovative DoA Biochips for Rapid Drug Screening II-41
Randox Launches Revolutionary Biochip Analyser for Multiple
Cardiac Testing II-41
Febit Unveils Biochip for DNA/RNA Detection and Enrichment on
Mouse Genome II-42
Veredus Laboratories Launches Portable Test Kit for H1N1 Flu II-42
Randox Develops Multi Marker Cardiac Biochip Array for MI
Diagnosis II-42
VigeneTech and CapitalBio Launch Completely Integrated
Microarray Solution Platform II-43
8. PRODUCT INNOVATIONS/INTRODUCTIONS - A HISTORIC PERSPECTIVE BUILDER II-44
Randox Introduces New Biochip Array for CAMs Testing II-44
Cellix Announces Global Launch of VenaEC Biochip II-44
Decision Biomarkers Rolls Out AVANTRA™ Biomarker Workstation
System II-44
Osaka Develops Biocompatible Monomers for Biochips II-45
Iris BioTechnologies Launches New Nano-Biochip II-45
Affymetrix Introduces Complete Cytogenetic Solution II-45
Agilent Unveils 244K CGH Micro-Array II-46
Randox Unveils World's First Protein Biochip II-46
Randox Introduces Thyroid Array Biochip II-46
Sigma Launches ChIP Kit II-46
Randox Develops Biochip for Synthetic Steroids II-47
US and Czech Scientists to Develop Biochips for Detecting Cancer II-47
Manchester University Researchers Develop New Protein Chips
Manufacturing Procedure II-47
febit Introduces New Geniom Biochip II-48
Agilent Introduces Additions to the HPLC-Chip Line for Proteomics II-49
Progenika Develops BLOODchip II-49
Roche Introduces Gene Expression Services and Arrays II-49
Stratos Biosystems Develops New EC-Affinity Biochips II-50
Affymetrix Unveils Affymetrix GeneChip Command Console Software II-50
Affymetrix Introduces GeneChip Mouse and Rat Gene 1.0 ST Arrays II-50
Affymetrix Unveils Genome-Wide Human SNP Array 6.0 II-51
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